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Tsung-Ying Chen Selected Research

Brain Infarction

2/2012Nicotinamide inhibits nuclear factor-kappa B translocation after transient focal cerebral ischemia.
4/2011Melatonin protects against transient focal cerebral ischemia in both reproductively active and estrogen-deficient female rats: the impact of circulating estrogen on its hormetic dose-response.
11/2010Melatonin inhibits postischemic matrix metalloproteinase-9 (MMP-9) activation via dual modulation of plasminogen/plasmin system and endogenous MMP inhibitor in mice subjected to transient focal cerebral ischemia.
6/2009Delayed treatment with carboxy-PTIO permits a 4-h therapeutic window of opportunity and prevents against ischemia-induced energy depletion following permanent focal cerebral ischemia in mice.
11/2008Melatonin decreases matrix metalloproteinase-9 activation and expression and attenuates reperfusion-induced hemorrhage following transient focal cerebral ischemia in rats.
4/2007Intravenous administration of melatonin reduces the intracerebral cellular inflammatory response following transient focal cerebral ischemia in rats.
8/2006Delayed treatment with nicotinamide inhibits brain energy depletion, improves cerebral microperfusion, reduces brain infarct volume, but does not alter neurobehavioral outcome following permanent focal cerebral ischemia in Sprague Dawley rats.
4/2006Melatonin attenuates the postischemic increase in blood-brain barrier permeability and decreases hemorrhagic transformation of tissue-plasminogen activator therapy following ischemic stroke in mice.
6/2005Delayed treatment with magnesium: reduction of brain infarction and improvement of electrophysiological recovery following transient focal cerebral ischemia in rats.
10/2004Effects of combined estrogen and progesterone on brain infarction in reproductively senescent female rats.
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Tsung-Ying Chen Research Topics

Disease

19Brain Ischemia (Cerebral Ischemia)
03/2014 - 06/2002
12Infarction (Infarctions)
03/2014 - 06/2002
11Ischemic Stroke
02/2012 - 06/2005
11Brain Infarction
02/2012 - 06/2002
10Stroke (Strokes)
03/2014 - 10/2004
9Parkinson Disease (Parkinson's Disease)
12/2021 - 08/2008
7Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome)
05/2011 - 12/2003
6Ischemia
06/2009 - 12/2003
2Inflammation (Inflammations)
09/2012 - 10/2009
2Diaschisis
05/2011 - 01/2004
2Ankylosing Spondylitis
12/2010 - 06/2008
2Reperfusion Injury
10/2009 - 01/2004
2Hemorrhage
03/2009 - 11/2008
1Cerebral Hemorrhage
10/2019
1Neuroinflammatory Diseases
10/2019
1Leukemia
01/2018
1Neoplasms (Cancer)
01/2017
1Meningioma (Meningiomas)
01/2017
1Insulin Resistance
03/2016
1Pain (Aches)
10/2015
1Body Weight (Weight, Body)
09/2012
1Encephalitis (Encephalitis, Rasmussen)
09/2012
1Meningitis
09/2012
1Surgical Wound Infection
05/2011
1Edema (Dropsy)
10/2009
1Hemorrhagic Stroke
09/2009
1Thrombosis (Thrombus)
09/2009
1Endoleak
03/2009
1Rupture
03/2009
1False Aneurysm (Pseudoaneurysm)
03/2009
1Brain Edema (Cerebral Edema)
11/2008
1Laryngismus (Laryngospasm)
06/2008
1Hyperthermia
08/2006

Drug/Important Bio-Agent (IBA)

10MelatoninIBA
03/2014 - 01/2004
4Matrix Metalloproteinase 9 (Gelatinase B)IBA
03/2014 - 11/2008
4Halothane (Fluothane)FDA Link
05/2011 - 12/2003
3Opioid Analgesics (Opioids)IBA
10/2015 - 12/2003
3Proteins (Proteins, Gene)FDA Link
03/2014 - 10/2009
3cinnamophilinIBA
05/2011 - 08/2005
2Sevoflurane (Ultane)FDA LinkGeneric
01/2021 - 01/2020
2LipopolysaccharidesIBA
01/2018 - 09/2012
2Glutamic Acid (Glutamate)FDA Link
03/2014 - 01/2012
2Niacinamide (Nicotinamide)FDA LinkGeneric
02/2012 - 08/2006
2magnololIBA
01/2012 - 10/2009
2Estrogens (Estrogen)FDA Link
04/2011 - 10/2004
2AntioxidantsIBA
04/2011 - 05/2009
2Adenosine Triphosphate (ATP)IBA
06/2009 - 08/2006
2Nitric Oxide (Nitrogen Monoxide)FDA Link
06/2009 - 09/2006
21,3- dihydroxy- 4,4,5,5- tetramethyl- 2- (4- carboxyphenyl)tetrahydroimidazole (NOR 1)IBA
06/2009 - 09/2006
2Oxygen (Dioxygen)IBA
05/2009 - 06/2008
2Tissue Plasminogen Activator (Alteplase)FDA Link
09/2006 - 04/2006
2Neuroprotective AgentsIBA
09/2006 - 12/2003
2Superoxides (Superoxide)IBA
09/2006 - 08/2005
21- (3,4- dichlorophenyl)acetyl- 2- (1- pyrrolidinyl)methylpiperidineIBA
05/2004 - 12/2003
1Desflurane (I 653)FDA Link
01/2021
1Proteasome Endopeptidase Complex (Proteasome)IBA
10/2019
1NigericinIBA
01/2018
1DNA (Deoxyribonucleic Acid)IBA
01/2017
1SuspensionsIBA
01/2017
1Pharmaceutical PreparationsIBA
04/2016
1TrehaloseIBA
03/2016
1Insulin (Novolin)FDA Link
03/2016
1GAP-43 Protein (GAP 43 Protein)IBA
03/2014
1NF-kappa B (NF-kB)IBA
02/2012
1Anti-Bacterial Agents (Antibiotics)IBA
05/2011
1Estradiol (Delestrogen)FDA LinkGeneric
04/2011
1Anesthetics (Anesthetic Agents)IBA
01/2011
1Matrix Metalloproteinase InhibitorsIBA
11/2010
1FibrinolysinFDA Link
11/2010
1Laminin (Merosin)IBA
11/2010
1PlasminogenIBA
11/2010
1Propofol (Diprivan)FDA LinkGeneric
09/2009
1ImidazolinesIBA
06/2009
1Glucose (Dextrose)FDA LinkGeneric
05/2009
1Matrix Metalloproteinases (MMPs)IBA
11/2008
1Inhalation AnestheticsIBA
08/2008
1NeurotoxinsIBA
09/2006
13-nitrotyrosineIBA
09/2006
1Adenosine Monophosphate (AMP)IBA
08/2006
1Adenine NucleotidesIBA
08/2006
1Adenosine (Adenocard)FDA LinkGeneric
08/2006
1Adenosine Diphosphate (ADP)IBA
08/2006
1Arginine Vasopressin (Argipressin)IBA
05/2006
1salicylhydroxamic acid (SHAM)IBA
05/2006
1Mannitol (Osmitrol)FDA LinkGeneric
05/2006
1AnionsIBA
08/2005

Therapy/Procedure

9Deep Brain Stimulation
12/2021 - 08/2008
6General Anesthesia
01/2020 - 12/2010
5Treatment Delay
06/2009 - 06/2002
3Local Anesthesia
01/2020 - 04/2016
3Thrombolytic Therapy
11/2010 - 04/2007
3Therapeutics
06/2009 - 06/2002
2Anesthesia
12/2021 - 06/2008
2Intravenous Administration
04/2007 - 01/2004
1Electrodes (Electrode)
01/2020
1Craniotomy
09/2009
1Stents
03/2009
1Tracheostomy
03/2009
1Microelectrodes
08/2008
1Carotid Endarterectomy
06/2005